Failure
The current measure of success in vasectomy reversal surgery is achievement of a pregnancy. There are several reasons why a vasectomy reversal may fail to achieve this:
A pregnancy involves two partners. Although the count and quality of sperm may be sufficiently high after vasectomy reversal surgery, female fertility factors may play an indirect role in pregnancy success. If the female partner’s age is >35 years old, the couple should consider a female factor evaluation to determine if they have adequate reproductive potential before a vasectomy reversal is undertaken. This evaluation can be done by a gynecologist and should include a cycle day 3 FSH and estradiol levels, an assessment of menstrual cycle regularity, and a hysterosalpingogram to evaluate for fibroids.
Approximately 50%-80% of men who have had vasectomies develop a reaction against their own sperm (i.e., antisperm antibodies). High levels of these proteins directed against sperm may impair fertility, either by making it hard for sperm to swim to the egg or by interrupting the way the sperm must interact with the egg. Sperm-bound antibodies are usually assessed >6 months after the vasectomy reversal if no pregnancy has ensued. Treatment options include steroid treatment, intrauterine insemination (IUI) and in vitro fertilization (IVF) techniques.
Occasionally, scar tissue develops at the site where the vas deferens is reconnected, causing a blockage. Depending on the physician, this occurs in 5-10% of vasovasostomies and up to 35% of vasoepididymostomies. Depending on when it occurs, it may be treated with anti-inflammatory medication or could necessitate repeat vasectomy reversal surgery.
If an epididymal blowout has occurred and is not discovered at the time of vasectomy reversal surgery, the vasectomy reversal will probably fail. In this case, a vasoepididymostomy would need to be performed.
When the vas deferens has been blocked for a long time, the epididymis is adversely affected by elevated pressure. As sperm are nurtured to maturity within the normal epididymis, sperm counts may be sufficiently high to achieve a pregnancy, but sperm movement may be poor. Antioxidants, vitamins (A, C and E), or other supplements are recommended by some centers after vasectomy reversal for this reason. Some patients gradually recover from this epididymal dysfunction. Those patients whose sperm continue to have problems may require IVF to achieve a pregnancy.
Complications
In general, vasectomy reversal is a safe procedure and complication rates are low. There are small chances of infection or bleeding, the latter of which can result in a hematoma or blood clot in the scrotum that needs surgical drainage. If there is significant scar tissue encountered during the vasectomy reversal, fluid other than blood (seroma) can also accumulate in a small number of cases. Painful granulomas, caused by leaking sperm, can develop near the surgical site in some cases. Very rare complications include compartment syndrome or deep venous thrombosis from prolonged positioning, testis atrophy due to damaged blood supply, and reactions to anesthesia.
The current measure of success in vasectomy reversal surgery is achievement of a pregnancy. There are several reasons why a vasectomy reversal may fail to achieve this:
A pregnancy involves two partners. Although the count and quality of sperm may be sufficiently high after vasectomy reversal surgery, female fertility factors may play an indirect role in pregnancy success. If the female partner’s age is >35 years old, the couple should consider a female factor evaluation to determine if they have adequate reproductive potential before a vasectomy reversal is undertaken. This evaluation can be done by a gynecologist and should include a cycle day 3 FSH and estradiol levels, an assessment of menstrual cycle regularity, and a hysterosalpingogram to evaluate for fibroids.
Approximately 50%-80% of men who have had vasectomies develop a reaction against their own sperm (i.e., antisperm antibodies). High levels of these proteins directed against sperm may impair fertility, either by making it hard for sperm to swim to the egg or by interrupting the way the sperm must interact with the egg. Sperm-bound antibodies are usually assessed >6 months after the vasectomy reversal if no pregnancy has ensued. Treatment options include steroid treatment, intrauterine insemination (IUI) and in vitro fertilization (IVF) techniques.
Occasionally, scar tissue develops at the site where the vas deferens is reconnected, causing a blockage. Depending on the physician, this occurs in 5-10% of vasovasostomies and up to 35% of vasoepididymostomies. Depending on when it occurs, it may be treated with anti-inflammatory medication or could necessitate repeat vasectomy reversal surgery.
If an epididymal blowout has occurred and is not discovered at the time of vasectomy reversal surgery, the vasectomy reversal will probably fail. In this case, a vasoepididymostomy would need to be performed.
When the vas deferens has been blocked for a long time, the epididymis is adversely affected by elevated pressure. As sperm are nurtured to maturity within the normal epididymis, sperm counts may be sufficiently high to achieve a pregnancy, but sperm movement may be poor. Antioxidants, vitamins (A, C and E), or other supplements are recommended by some centers after vasectomy reversal for this reason. Some patients gradually recover from this epididymal dysfunction. Those patients whose sperm continue to have problems may require IVF to achieve a pregnancy.
Complications
In general, vasectomy reversal is a safe procedure and complication rates are low. There are small chances of infection or bleeding, the latter of which can result in a hematoma or blood clot in the scrotum that needs surgical drainage. If there is significant scar tissue encountered during the vasectomy reversal, fluid other than blood (seroma) can also accumulate in a small number of cases. Painful granulomas, caused by leaking sperm, can develop near the surgical site in some cases. Very rare complications include compartment syndrome or deep venous thrombosis from prolonged positioning, testis atrophy due to damaged blood supply, and reactions to anesthesia.